2-[(3-Methylbenzyl)oxy]benzoic acid
2-[(3-Methylbenzyl)oxy]benzoic acid
CAS: 744242-83-9
Molecular Formula: C15H14O3
2-[(3-Methylbenzyl)oxy]benzoic acid - Names and Identifiers
| Name | 2-[(3-Methylbenzyl)oxy]benzoic acid |
| Synonyms | 2-[(3-Methylbenzyl)oxy]benzoic acid 2-[(3-Methylphenyl)methoxy]benzoic acid Benzoic acid, 2-[(3-methylphenyl)methoxy] |
| CAS | 744242-83-9 |
2-[(3-Methylbenzyl)oxy]benzoic acid - Physico-chemical Properties
| Molecular Formula | C15H14O3 |
| Molar Mass | 242.27 |
| Density | 1.193 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD05267697 |
2-[(3-Methylbenzyl)oxy]benzoic acid - Introduction
2-[(3-Methylbenzyl)oxy]benzoic acid is an organic compound with the chemical formula C16H14O3. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless crystalline solid
-Melting point: about 115-118 degrees Celsius
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dichloromethane, slightly soluble in water
-specific gravity: about 1.2-1.3g/cm³
Use:
- 2-[(3-Methylbenzyl)oxy]benzoic acid can be used as pharmaceutical intermediates, which has important application value in the synthesis of drugs.
Preparation Method:
2-[(3-Methylbenzyl)oxy]benzoic acid can be synthesized by the following steps:
1.3-methyl benzyl alcohol and benzoic acid are reacted by esterification to obtain 3-methyl phenyl benzoate.
2. A base-catalyzed acetal reaction of 3-methyl phenyl benzoate and sodium hydroxide was performed to obtain 2-[(3-methylphenyl) methoxy] benzaldehyde.
3. Finally, 2-[(3-methylphenyl) methoxy] benzaldehyde is oxidized to the target product 2-[(3-Methylphenyl) oxy]benzoic acid.
Safety Information:
Pay attention to the following safety precautions when using 2-[(3-Methylbenzol) oxy]benzoic acid:
-This compound may be irritating to the eyes, skin and respiratory system, so avoid contact when using it.
-Wear appropriate protective equipment such as gloves, goggles and protective clothing during handling and handling.
-avoid inhalation of its dust or vapor, pay attention to ensure that the operating place is well ventilated.
-Waste shall be disposed of in accordance with local regulations and shall not be dumped.
Nature:
-Appearance: Colorless crystalline solid
-Melting point: about 115-118 degrees Celsius
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dichloromethane, slightly soluble in water
-specific gravity: about 1.2-1.3g/cm³
Use:
- 2-[(3-Methylbenzyl)oxy]benzoic acid can be used as pharmaceutical intermediates, which has important application value in the synthesis of drugs.
Preparation Method:
2-[(3-Methylbenzyl)oxy]benzoic acid can be synthesized by the following steps:
1.3-methyl benzyl alcohol and benzoic acid are reacted by esterification to obtain 3-methyl phenyl benzoate.
2. A base-catalyzed acetal reaction of 3-methyl phenyl benzoate and sodium hydroxide was performed to obtain 2-[(3-methylphenyl) methoxy] benzaldehyde.
3. Finally, 2-[(3-methylphenyl) methoxy] benzaldehyde is oxidized to the target product 2-[(3-Methylphenyl) oxy]benzoic acid.
Safety Information:
Pay attention to the following safety precautions when using 2-[(3-Methylbenzol) oxy]benzoic acid:
-This compound may be irritating to the eyes, skin and respiratory system, so avoid contact when using it.
-Wear appropriate protective equipment such as gloves, goggles and protective clothing during handling and handling.
-avoid inhalation of its dust or vapor, pay attention to ensure that the operating place is well ventilated.
-Waste shall be disposed of in accordance with local regulations and shall not be dumped.
Last Update：2024-04-09 21:00:56
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